Amphetamine is a powerful stimulant that can have devastating physical and mental health effects. From nausea and tremors to increased blood pressure and heart rate, this drug can cause long-term damage if used in excess or without proper medical supervision. Learn more about how it affects the body here.

What is amphetamine?

Amphetamine is a type of synthetic stimulant drug that has been used in medical and recreational settings since the early 20th century. It is most often prescribed under brand names such as Adderall for the treatment of conditions like narcolepsy, ADHD, and depression, but it can also be abused illegally. It works by increasing dopamine levels in the brain and activating certain reward pathways that lead to feelings of pleasure and generally improved mental functioning.

How does it affect the body?

Amphetamine can have a variety of effects on the body, both short-term and long-term. In the short-term, people may experience increased heart rate and blood pressure, headaches, dry mouth, difficulty sleeping, nausea and vomiting, loss of appetite, increased energy and alertness, delusions of grandeur, paranoia and anxiety. In the long-term, repeated use can lead to dependency and addiction. Regular use can also potentially cause an irregular heartbeat or seizures as well as damage to organs such as the liver or heart.

What are the common side effects of amphetamine use?

Common short-term side effects of amphetamine use include increased heart rate and blood pressure, headaches, dry mouth, difficulty sleeping, nausea and vomiting, loss of appetite, increased energy and alertness, delusions of grandeur, paranoia and anxiety. In the long-term, repeated use can cause addiction or dependency as well as irregular heartbeats and seizures. It use can also damage organs such as the liver or heart over time.

Are there long-term risks associated with amphetamine abuse?

Yes, amphetamine abuse poses multiple long-term risks to abusers including addiction or dependence, organ damage and increased risk for heart and brain function issues. Long-term amphetamine abuse can also take a toll on mental health, leading to depression, worsened anxiety and an increased risk for psychosis.

How can I get help for an addiction?

If you or someone you know is struggling with an amphetamine addiction, professional help is essential. Treatment plans are individualized and can include a combination of medication-assisted treatment, cognitive behavioral therapy, and lifestyle changes. Addiction treatment professionals can provide structure and support to those seeking recovery from this powerful drug.

Neurotoxicity of methamphetamine

Methamphetamine, also known as meth, is a powerful and highly addictive substance known for its neurotoxic effects. It works by manipulating the brain’s chemistry and increasing levels of reactive oxygen species such as hydrogen peroxide, superoxide radicals, and hydroxyl radicals. Upon ingestion, it triggers an inflammatory response in microglial cells which leads to further changes in brain function and ultimately can cause damage to the nervous system. Source : Neurotoxicity of methamphetamine: Main effects and mechanisms.